CAMK2A 抗体 (pThr286)
(11 references)Quick Overview for CAMK2A 抗体 (pThr286) (ABIN361458)
抗原
See all CAMK2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr286
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特异性
- Specific for endogenous levels of the ~50 kDa α-CaM Kinase II and the ~60 kDa β-CaM Kinase II proteins phosphorylated at Thr286. Immunolabeling is completely eliminated by treatment with λ-phosphatase.
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交叉反应
- 人, 小鼠, 兔, 大鼠
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预测反应
- human, Xenopus
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产品特性
- Our CaM Kinase II (Thr286) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects CaM Kinase II (Thr286) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC.
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纯化方法
- Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.
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免疫原
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr286 of rat CaMKII, conjugated to keyhole limpet hemocyanin (KLH).
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亚型
- IgG
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anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (AA 1-478) antibody
CAMK2A 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (AA 305-410) antibodyCAMK2A 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (AA 305-410) antibodyCAMK2A 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C12 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (AA 305-410) antibodyCAMK2A 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2C11 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (AA 321-478) antibodyCAMK2A 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) antibodyMicroarray verified CAMK2A 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB443776 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (pThr305) antibodyCAMK2A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (AA 321-478) antibodyCAMK2A 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (pThr305) antibodyCAMK2A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (pThr286) antibodyCAMK2A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Dilution Range: WB Brain: 1:1000
Dilution Range: WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
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储存条件
- -20 °C
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储存方法
- Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
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有效期
- 12 months
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: "Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes." in: Nature communications, Vol. 9, Issue 1, pp. 3434, (2018) (PubMed).
: "Kinetics of Endogenous CaMKII Required for Synaptic Plasticity Revealed by Optogenetic Kinase Inhibitor." in: Neuron, Vol. 94, Issue 1, pp. 37-47.e5, (2017) (PubMed).
: "Necessary, but not sufficient: insights into the mechanisms of mGluR mediated long-term depression from a rat model of early life seizures." in: Neuropharmacology, Vol. 84, pp. 1-12, (2014) (PubMed).
: "Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles." in: Molecular biology of the cell, Vol. 23, Issue 20, pp. 4065-78, (2012) (PubMed).
: "A significant but rather mild contribution of T286 autophosphorylation to Ca2+/CaM-stimulated CaMKII activity." in: PLoS ONE, Vol. 7, Issue 5, pp. e37176, (2012) (PubMed).
: "Nonsynaptic NMDA receptors mediate activity-dependent plasticity of gap junctional coupling in the AII amacrine cell network." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 20, pp. 6747-59, (2012) (PubMed).
: "Preserving protein profiles in tissue samples: differing outcomes with and without heat stabilization." in: Journal of neuroscience methods, Vol. 196, Issue 1, pp. 99-106, (2011) (PubMed).
: "Alterations in AMPA receptor subunits and TARPs in the rat nucleus accumbens related to the formation of Ca²?-permeable AMPA receptors during the incubation of cocaine craving." in: Neuropharmacology, Vol. 61, Issue 7, pp. 1141-51, (2011) (PubMed).
: "CaMKII autonomy is substrate-dependent and further stimulated by Ca2+/calmodulin." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17930-7, (2010) (PubMed).
: "Effective post-insult neuroprotection by a novel Ca(2+)/ calmodulin-dependent protein kinase II (CaMKII) inhibitor." in: The Journal of biological chemistry, Vol. 285, Issue 27, pp. 20675-82, (2010) (PubMed).
: "Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway." in: The Journal of biological chemistry, Vol. 282, Issue 46, pp. 33305-12, (2007) (PubMed).
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: "Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes." in: Nature communications, Vol. 9, Issue 1, pp. 3434, (2018) (PubMed).
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- CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
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别名
- CaM Kinase II
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背景
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Synonyms: Calcium/calmodulin dependent protein kinase II alpha antibody, Calcium/calmodulin dependent protein kinase II beta antibody, Calcium/calmodulin dependent protein kinase II delta antibody, Calcium/calmodulin dependent protein kinase II gamma antibody, Calcium/calmodulin-dependent protein kinase type II subunit alpha antibody, CaM kinase II alpha antibody, CaM kinase II antibody, CaM kinase II beta antibody, CaM kinase II delta antibody, CaM kinase II gamma antibody, CaM kinase II subunit alpha antibody, CaMK-II subunit alpha antibody, CAMK2 antibody, Camk2a antibody, CAMK2B antibody, CAMK2D antibody, CAMK2G antibody, CAMKA antibody, KCC2A_HUMAN antibody
Description Logic: Our CaM Kinase II (Thr286) rabbit polyclonal phosphospecific primary antibody is produced . It detects CaM Kinase II (Thr286) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC.
Gene Name Alternatives: CAMK2A/B
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分子量
- 50 kDa/60 kDa
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基因ID
- 25400
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UniProt
- P11275
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途径
- WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction
抗原
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